Reactome | histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen

Schema > Reaction > Entries

histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen Show undefined attributes

authored	[InstanceEdit:158720] D'Eustachio, P, 2005-02-05 20:25:20
category	dissociation
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:158723] D'Eustachio, P, 2005-02-05 20:26:06
dbId	158721
displayName	histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen
edited	[InstanceEdit:165080] D'Eustachio, P, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-75205] Dissolution of Fibrin Clot - Homo sapiens
followingEvent	[Reaction:R-HSA-158784] crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen - Homo sapiens
input	[Complex:R-HSA-158703] histidine-rich glycoprotein:plasminogen [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:158717] Amino acid sequence of human histidine-rich glycoprotein derived from the nucleotide sequence of its cDNA [LiteratureReference:158716] Isolation and characterization of a human plasma protein with affinity for the lysine binding sites in plasminogen. Role in the regulation of fibrinolysis and identification as histidine-rich glycoprotein. [LiteratureReference:158715] HRG Tokushima: molecular and cellular characterization of histidine-rich glycoprotein (HRG) deficiency
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen
orthologousEvent	[Reaction:R-GGA-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Gallus gallus [Reaction:R-XTR-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Xenopus tropicalis [Reaction:R-DRE-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Danio rerio [Reaction:R-SSC-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Sus scrofa [Reaction:R-BTA-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Bos taurus [Reaction:R-CFA-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Canis familiaris [Reaction:R-RNO-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Rattus norvegicus [Reaction:R-MMU-158721] histidine-rich glycoprotein:plasminogen <-> histidine-rich glycoprotein + plasminogen - Mus musculus
output	[EntityWithAccessionedSequence:R-HSA-158699] HRG [extracellular region] [EntityWithAccessionedSequence:R-HSA-158701] PLG(20-810) [extracellular region]
releaseDate	2005-04-11
reverseReaction	[Reaction:R-HSA-158722] histidine-rich glycoprotein + plasminogen <-> histidine-rich glycoprotein:plasminogen
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-158721
summation	[Summation:158719] Plasminogen reversibly binds histidine-rich glycoprotein (HR...

Referrals

(hasEvent)	[Pathway:R-HSA-75205] Dissolution of Fibrin Clot
(precedingEvent)	[Reaction:R-HSA-158784] crosslinked fibrin multimer:tissue plasminogen activator (one-chain) + plasminogen -> crosslinked fibrin multimer:tissue plasminogen activator (one-chain):plasminogen