Reactome | ADAM10 [plasma membrane]

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ADAM10 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-3928569] EFNAs:ADAM10 [plasma membrane] - Homo sapiens
created	[InstanceEdit:157219] Jassal, B, 2004-12-17 11:53:55
dbId	157237
displayName	ADAM10 [plasma membrane]
endCoordinate	748
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-157237] ADAM10 [plasma membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-157237] ADAM10 [plasma membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-157237] ADAM10 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-157237] ADAM10 [plasma membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-157237] ADAM10 [plasma membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-157237] ADAM10 [plasma membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-157237] ADAM10 [plasma membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-157237] ADAM10 [plasma membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-157237] ADAM10 [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-157237] ADAM10 [plasma membrane] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-4224013] ADAM10, ADAM15 [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-2473494] Collagen type XVII sheddases [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-6806323] Specific granule membrane proteins [plasma membrane] - Homo sapiens [DefinedSet:R-HSA-6806434] Tertiary granule membrane proteins [plasma membrane] - Homo sapiens
modified	[InstanceEdit:3928382] Garapati, P V, 2013-07-22
name	ADAM10 ADAM 10 metalloprotease KUZ
producedByEvent	[BlackBoxEvent:R-HSA-3928660] ADAM10 cleaves EFNAs - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:O14672] UniProt:O14672 ADAM10
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-157237
startCoordinate	214
updateTrackers	[UpdateTracker:9873493] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v43:[addName] [UpdateTracker:9871551] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v40:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9888505] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v46:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9873493] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v43:[addName] [UpdateTracker:9871551] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v40:[modifyEndCoordinate, modifyStartCoordinate] [UpdateTracker:9888505] Update Tracker - [EntityWithAccessionedSequence:157237] ADAM10 [plasma membrane] - v46:[addName]
(hasMember)	[DefinedSet:R-HSA-2473494] Collagen type XVII sheddases [plasma membrane] [DefinedSet:R-HSA-4224013] ADAM10, ADAM15 [plasma membrane] [DefinedSet:R-HSA-6806434] Tertiary granule membrane proteins [plasma membrane] [DefinedSet:R-HSA-6806323] Specific granule membrane proteins [plasma membrane] [CandidateSet:R-HSA-1852617] ADAM10/17 [plasma membrane]
(output)	[BlackBoxEvent:R-HSA-3928660] ADAM10 cleaves EFNAs
(hasComponent)	[Complex:R-HSA-3928569] EFNAs:ADAM10 [plasma membrane] [Complex:R-HSA-157186] ADAM10:Zn2+ [plasma membrane]
(activeUnit)	[CatalystActivity:3928655] metallopeptidase activity of EPHAs:EFNAs:ADAM10 [plasma membrane]

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