Reactome | FURIN [Golgi membrane]

Schema > EntityWithAccessionedSequence > Entries

FURIN [Golgi membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5693097] endopeptidase activity of FURIN [Golgi membrane] [CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]
compartment	[Compartment:20699] Golgi membrane
componentOf	[Complex:R-HSA-9954216] FURIN:GGC-GBP5 dimer:GTP [Golgi membrane] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-9736953] FURIN translocates to the plasma membrane - Homo sapiens [Reaction:R-HSA-9954252] GGC-GBP2, GGC-GBP5 bind furin - Homo sapiens [Reaction:R-HSA-9954252] GGC-GBP2, GGC-GBP5 bind furin - Homo sapiens
created	[InstanceEdit:157021] Jassal, B, 2004-12-15 13:08:03
dbId	157049
displayName	FURIN [Golgi membrane]
endCoordinate	794
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-157049] FURIN [Golgi membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-157049] FURIN [Golgi membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-157049] FURIN [Golgi membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-157049] FURIN [Golgi membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-157049] FURIN [Golgi membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-157049] furina [Golgi membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-157049] furin [Golgi membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-157049] FURIN [Golgi membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-157049] Fur1 [Golgi membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-157049] FURIN [Golgi membrane] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-SPO-157049] krp1 [Golgi membrane] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-157049] FURIN [Golgi membrane] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-PFA-157049] FURIN [Golgi membrane] - Plasmodium falciparum [EntityWithAccessionedSequence:R-PFA-157049-2] SUB2 [Golgi membrane] - Plasmodium falciparum [DefinedSet:R-PFA-157049-3] Homologues of FURIN [Golgi membrane] - Plasmodium falciparum
literatureReference	[LiteratureReference:159838] Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage
maxDepth	1
memberOf	[CandidateSet:R-HSA-9933718] FURIN, PCSK7,(PCSK6) [Golgi membrane] - Homo sapiens
modified	[InstanceEdit:1852563] Orlic-Milacic, M, 2011-10-28
name	FURIN Furin
producedByEvent	[BlackBoxEvent:R-HSA-9733203] FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P09958] UniProt:P09958 FURIN
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-157049
startCoordinate	108
updateTrackers	[UpdateTracker:9870590] Update Tracker - [EntityWithAccessionedSequence:157049] FURIN [Golgi membrane] - v38:[addName] [UpdateTracker:9871207] Update Tracker - [EntityWithAccessionedSequence:157049] FURIN [Golgi membrane] - v39:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9870590] Update Tracker - [EntityWithAccessionedSequence:157049] FURIN [Golgi membrane] - v38:[addName] [UpdateTracker:9871207] Update Tracker - [EntityWithAccessionedSequence:157049] FURIN [Golgi membrane] - v39:[modifyName]
(physicalEntity)	[CatalystActivity:5693097] endopeptidase activity of FURIN [Golgi membrane] [CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]
(hasComponent)	[Complex:R-HSA-9954216] FURIN:GGC-GBP5 dimer:GTP [Golgi membrane] [Complex:R-HSA-9954213] FURIN:GGC-GBP2 dimer:GTP [Golgi membrane]
(input)	[Reaction:R-HSA-9954252] GGC-GBP2, GGC-GBP5 bind furin [BlackBoxEvent:R-HSA-9736953] FURIN translocates to the plasma membrane
(hasMember)	[CandidateSet:R-HSA-9933718] FURIN, PCSK7,(PCSK6) [Golgi membrane]
(output)	[BlackBoxEvent:R-HSA-9733203] FURIN gene transcription is stimulated by SMAD2/SMAD3:SMAD4

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