Reactome | EGF:Ligand-responsive EGFR mutants dimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1500848] Orlic-Milacic, Marija, 2011-08-22
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	1500847
disease	[Disease:1500689] cancer
displayName	EGF:Ligand-responsive EGFR mutants dimer [plasma membrane]
hasComponent	2 × [DefinedSet:R-HSA-1220578] EGF:Ligand-responsive EGFR mutants:HSP90:CDC37 [plasma membrane]
inDisease	true
isChimeric	false
maxDepth	5
memberOf	[DefinedSet:R-HSA-1220582] Active dimers of ligand-responsive EGFR mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:2213009] Matthews, L, 2012-04-27
name	EGF:Ligand-responsive EGFR mutants dimer
producedByEvent	[Reaction:R-HSA-1220613] EGF-induced dimerization of ligand-responsive EGFR mutants - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1500847
updateTrackers	[UpdateTracker:9873120] Update Tracker - [Complex:1500847] EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9872266] Update Tracker - [Complex:1500847] EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] - v41:[removeCompartment, updateContainedComponent]

(updatedInstance)	[UpdateTracker:9873120] Update Tracker - [Complex:1500847] EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] - v42:[updateContainedComponent] [UpdateTracker:9872266] Update Tracker - [Complex:1500847] EGF:Ligand-responsive EGFR mutants dimer [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
(output)	[Reaction:R-HSA-1220613] EGF-induced dimerization of ligand-responsive EGFR mutants
(hasMember)	[DefinedSet:R-HSA-1220582] Active dimers of ligand-responsive EGFR mutants [plasma membrane]

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