Reactome | PA is converted to CDP-DAG by CDS2

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PA is converted to CDP-DAG by CDS2 Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524097] phosphatidate cytidylyltransferase activity of CDS2 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1483214] Williams, MG, 2011-08-12
dbId	1483165
displayName	PA is converted to CDP-DAG by CDS2
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483148] Synthesis of PG - Homo sapiens
followingEvent	[Reaction:R-HSA-1482939] CDP-DAG is converted to PGP by PGS1 - Homo sapiens [Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1 - Homo sapiens
input	[SimpleEntity:R-ALL-110577] CTP [mitochondrial matrix] [SimpleEntity:R-ALL-1524101] PA [mitochondrial inner membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482952] The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content [LiteratureReference:1483032] Cardiolipin is synthesized on the matrix side of the inner membrane in rat liver mitochondria [LiteratureReference:1483143] Participation of the microsomal CDP-diglycerides in the mitochondrial biosynthesis of phosphatidylglycerol
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	PA is converted to CDP-DAG by CDS2
orthologousEvent	[Reaction:R-PFA-1483165] PA is converted to CDP-DAG by CDS2 - Plasmodium falciparum [Reaction:R-SCE-1483165] PA is converted to CDP-DAG by CDS2 - Saccharomyces cerevisiae [Reaction:R-SPO-1483165] PA is converted to CDP-DAG by CDS2 - Schizosaccharomyces pombe [Reaction:R-DDI-1483165] PA is converted to CDP-DAG by CDS2 - Dictyostelium discoideum [Reaction:R-CEL-1483165] PA is converted to CDP-DAG by CDS2 - Caenorhabditis elegans [Reaction:R-DME-1483165] PA is converted to CDP-DAG by CDS2 - Drosophila melanogaster [Reaction:R-GGA-1483165] PA is converted to CDP-DAG by CDS2 - Gallus gallus [Reaction:R-XTR-1483165] PA is converted to CDP-DAG by CDS2 - Xenopus tropicalis [Reaction:R-DRE-1483165] PA is converted to CDP-DAG by CDS2 - Danio rerio [Reaction:R-SSC-1483165] PA is converted to CDP-DAG by CDS2 - Sus scrofa [Reaction:R-BTA-1483165] PA is converted to CDP-DAG by CDS2 - Bos taurus [Reaction:R-CFA-1483165] PA is converted to CDP-DAG by CDS2 - Canis familiaris [Reaction:R-RNO-1483165] PA is converted to CDP-DAG by CDS2 - Rattus norvegicus [Reaction:R-MMU-1483165] PA is converted to CDP-DAG by CDS2 - Mus musculus
output	[SimpleEntity:R-ALL-1524064] CDP-DAG [mitochondrial inner membrane] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix]
precedingEvent	[Reaction:R-HSA-1483099] PA translocates from the outer to the inner mitochondrial membrane - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1483165
summation	[Summation:1482942] At the inner mitochondrial (IM) membrane, phosphatidate cyti...

Referrals

(hasEvent)	[Pathway:R-HSA-1483148] Synthesis of PG
(precedingEvent)	[Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1 [Reaction:R-HSA-1482939] CDP-DAG is converted to PGP by PGS1

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