Reactome | 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C

Schema > Reaction > Entries

1-acyl LPE is hydrolyzed to GPETA by PLA2G4C Show undefined attributes

authored	[InstanceEdit:1602345] Williams, MG, 2011-09-14
catalystActivity	[CatalystActivity:1524030] phosphatidylcholine lysophospholipase A1 activity of PLA2G4C [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:1482525] Williams, MG, 2011-08-12
dbId	1482571
displayName	1-acyl LPE is hydrolyzed to GPETA by PLA2G4C
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
eventOf	[Pathway:R-HSA-1483152] Hydrolysis of LPE - Homo sapiens
followingEvent	[Reaction:R-HSA-1483107] GPETA is hydrolyzed to ETA and G3P by GPCPD1 - Homo sapiens
input	[SimpleEntity:R-ALL-1498738] 1-acyl LPE [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-29356] H2O [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1482631] Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma) [LiteratureReference:1482624] Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma)
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	1-acyl LPE is hydrolyzed to GPETA by PLA2G4C
orthologousEvent	[Reaction:R-SCE-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Saccharomyces cerevisiae [Reaction:R-SPO-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Schizosaccharomyces pombe [Reaction:R-DDI-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Dictyostelium discoideum [Reaction:R-DRE-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Danio rerio [Reaction:R-RNO-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Rattus norvegicus [Reaction:R-MMU-1482571] 1-acyl LPE is hydrolyzed to GPETA by PLA2G4C - Mus musculus
output	[SimpleEntity:R-ALL-1524023] GPETA [cytosol] [SimpleEntity:R-ALL-1524021] LCFA(-) [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-1482884] PE is hydrolyzed to 1-acyl LPE by PLA2[2] - Homo sapiens [Reaction:R-HSA-1482887] PE is hydrolyzed to 1-acyl LPE by PLA2[3] - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1482571
summation	[Summation:1482674] At the endoplasmic reticulum (ER) membrane, membrane-bound c...

Referrals

(hasEvent)	[Pathway:R-HSA-1483152] Hydrolysis of LPE
(precedingEvent)	[Reaction:R-HSA-1483107] GPETA is hydrolyzed to ETA and G3P by GPCPD1