Reactome | Carbonic anhydrase dehydrates bicarbonate (mitochondria)

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Carbonic anhydrase dehydrates bicarbonate (mitochondria) Show undefined attributes

authored	[InstanceEdit:1475033] May, B, 2011-08-06
catalystActivity	[CatalystActivity:1475031] carbonate dehydratase activity of CA5A,B:Zinc [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:1475019] May, B, 2011-08-07
crossReference	[DatabaseIdentifier:12668148] RHEA:10749
dbId	1475028
displayName	Carbonic anhydrase dehydrates bicarbonate (mitochondria)
edited	[InstanceEdit:1475033] May, B, 2011-08-06
eventOf	[Pathway:R-HSA-1475029] Reversible hydration of carbon dioxide - Homo sapiens
input	[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-29896] HCO3- [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1237274] Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors [LiteratureReference:1237252] Carbonic anhydrase inhibitors: inhibition of human and murine mitochondrial isozymes V with anions [LiteratureReference:1237492] Carbonic anhydrase inhibitors: the inhibition profiles of the human mitochondrial isoforms VA and VB with anions are very different [LiteratureReference:1237227] Human mitochondrial carbonic anhydrase VB. cDNA cloning, mRNA expression, subcellular localization, and mapping to chromosome x [LiteratureReference:1237221] Human mitochondrial carbonic anhydrase: cDNA cloning, expression, subcellular localization, and mapping to chromosome 16 [LiteratureReference:1243058] Structure and mechanism of carbonic anhydrase
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Carbonic anhydrase dehydrates bicarbonate (mitochondria)
orthologousEvent	[Reaction:R-CEL-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Caenorhabditis elegans [Reaction:R-DME-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Drosophila melanogaster [Reaction:R-GGA-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Gallus gallus [Reaction:R-XTR-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Xenopus tropicalis [Reaction:R-DRE-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Danio rerio [Reaction:R-SSC-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Sus scrofa [Reaction:R-BTA-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Bos taurus [Reaction:R-CFA-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Canis familiaris [Reaction:R-RNO-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Rattus norvegicus [Reaction:R-MMU-1475028] Carbonic anhydrase dehydrates bicarbonate (mitochondria) - Mus musculus
output	[SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-113521] H2O [mitochondrial matrix]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2252565] Jassal, B, 2012-05-16 [InstanceEdit:2252567] Silverman, DN, 2012-05-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1475028
summation	[Summation:1475024] Carbonic anhydrase VA (CA5A, Nagao et al. 1993, Franchi et a...

Referrals

(hasEvent)	[Pathway:R-HSA-1475029] Reversible hydration of carbon dioxide
(reverseReaction)	[Reaction:R-HSA-1475032] Carbonic anhydrase hydrates carbon dioxide (mitochondria)

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