Reactome | JAK2:SFKS:p-KIT complex [plasma membrane]

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JAK2:SFKS:p-KIT complex [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:2447206] protein tyrosine kinase activity of JAK2:SFKS:p-KIT complex [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-1433418] Phosphorylation of JAK2 - Homo sapiens
created	[InstanceEdit:1433498] Garapati, P V, 2011-07-11
dbId	1433493
displayName	JAK2:SFKS:p-KIT complex [plasma membrane]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-210620] JAK2 [cytosol] [Complex:R-HSA-205271] SFKs:p-KIT complex [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Mus musculus [Complex:R-RNO-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Rattus norvegicus [Complex:R-CFA-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Canis familiaris [Complex:R-BTA-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Bos taurus [Complex:R-SSC-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Sus scrofa [Complex:R-DRE-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Danio rerio [Complex:R-XTR-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	5
modified	[InstanceEdit:2231000] Matthews, L, 2012-05-07
name	JAK2:SFKS:p-KIT complex
producedByEvent	[Reaction:R-HSA-1433451] JAK2 binds to p-KIT - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1433493
updateTrackers	[UpdateTracker:9877822] Update Tracker - [Complex:1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - v44:[updateContainedComponent] [UpdateTracker:9872469] Update Tracker - [Complex:1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - v41:[removeCompartment, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9877822] Update Tracker - [Complex:1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - v44:[updateContainedComponent] [UpdateTracker:9872469] Update Tracker - [Complex:1433493] JAK2:SFKS:p-KIT complex [plasma membrane] - v41:[removeCompartment, updateContainedComponent]
(normalEntity)	[EntityFunctionalStatus:9670388] gain_of_function of KIT mutant dimers:SFKs:JAK2 [plasma membrane]
(output)	[Reaction:R-HSA-1433451] JAK2 binds to p-KIT
(input)	[Reaction:R-HSA-1433418] Phosphorylation of JAK2
(physicalEntity)	[CatalystActivity:2447206] protein tyrosine kinase activity of JAK2:SFKS:p-KIT complex [plasma membrane]

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