Reactome | PAOX:FAD oxidises NASPN to SPM

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PAOX:FAD oxidises NASPN to SPM Show undefined attributes

authored	[InstanceEdit:351144] Gopinathrao, G, 2008-05-21 15:52:50
catalystActivity	[CatalystActivity:141347] N(1)-acetylpolyamine oxidase activity of PAOX:FAD [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:141321] Jassal, B, 2004-09-16 09:57:59
crossReference	[DatabaseIdentifier:12668118] RHEA:25801 [DatabaseIdentifier:9955556] RHEA:25801
dbId	141351
displayName	PAOX:FAD oxidises NASPN to SPM
edited	[InstanceEdit:179407] Gopinathrao, G, 2006-04-27 13:13:48
eventOf	[Pathway:R-HSA-141334] PAOs oxidise polyamines to amines - Homo sapiens [Pathway:R-HSA-351200] Interconversion of polyamines - Homo sapiens
input	[SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix] [SimpleEntity:R-ALL-141323] NASPN [peroxisomal matrix] [SimpleEntity:R-ALL-113535] O2 [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:266172] Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	PAOX:FAD oxidises NASPN to SPM N(1)-acetylspermine + O2 + H2O => 3-acetamidopropanal + spermidine + H2O2
orthologousEvent	[Reaction:R-BTA-141351] PAOX:FAD oxidises NASPN to SPM - Bos taurus [Reaction:R-CEL-141351] PAOX:FAD oxidises NASPN to SPM - Caenorhabditis elegans [Reaction:R-DME-141351] PAOX:FAD oxidises NASPN to SPM - Drosophila melanogaster [Reaction:R-GGA-141351] PAOX:FAD oxidises NASPN to SPM - Gallus gallus [Reaction:R-DRE-141351] PAOX:FAD oxidises NASPN to SPM - Danio rerio [Reaction:R-SSC-141351] PAOX:FAD oxidises NASPN to SPM - Sus scrofa [Reaction:R-CFA-141351] PAOX:FAD oxidises NASPN to SPM - Canis familiaris [Reaction:R-RNO-141351] PAOX:FAD oxidises NASPN to SPM - Rattus norvegicus [Reaction:R-MMU-141351] PAOX:FAD oxidises NASPN to SPM - Mus musculus
output	[SimpleEntity:R-ALL-141327] 3AAPNAL [peroxisomal matrix] [SimpleEntity:R-ALL-113575] H2O2 [peroxisomal matrix] [SimpleEntity:R-ALL-141324] SPM [peroxisomal matrix]
precedingEvent	[BlackBoxEvent:R-HSA-351229] N-acetylated spermine (cytosol)=>N-acetylated spermine (peroxisomal) - Homo sapiens
releaseDate	2008-09-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:377465] D'Eustachio, P, 2008-06-12 14:43:38
revised	[InstanceEdit:5602271] Jassal, Bijay, 2014-06-23
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-141351
summation	[Summation:178962] Acetylated spermine (NASPN) is oxidised by the flavoenzyme p...
updateTrackers	[UpdateTracker:9786193] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v50:[modifyText] [UpdateTracker:9791786] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v25:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9786193] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v50:[modifyText] [UpdateTracker:9791786] Update Tracker - [Reaction:141351] PAOX:FAD oxidises NASPN to SPM - v25:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-141334] PAOs oxidise polyamines to amines [Pathway:R-HSA-351200] Interconversion of polyamines