Reactome | 12xCbxE-3D-F9(47-461) [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

12xCbxE-3D-F9(47-461) [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
consumedByEvent	[Reaction:R-HSA-9936467] factor IX -> factor IXa + factor IX activation peptide (kallikrein catalyst) - Homo sapiens [Reaction:R-HSA-158333] factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) - Homo sapiens [Reaction:R-HSA-9929051] TF:FVIIa+FIX -> TF:FVIIa:FIXa + FIX activation peptide (TF:F7a catalyst) - Homo sapiens
created	[InstanceEdit:140579] D'Eustachio, P, 2004-08-24 14:00:00
dbId	140886
displayName	12xCbxE-3D-F9(47-461) [extracellular region]
endCoordinate	461
hasModifiedResidue	[ModifiedResidue:140824] L-gamma-carboxyglutamic acid at 86 [ModifiedResidue:140835] L-gamma-carboxyglutamic acid at 82 [ModifiedResidue:140836] L-gamma-carboxyglutamic acid at 79 [ModifiedResidue:140878] L-gamma-carboxyglutamic acid at 76 [ModifiedResidue:140879] L-gamma-carboxyglutamic acid at 73 [ModifiedResidue:140880] L-gamma-carboxyglutamic acid at 72 [ModifiedResidue:140881] L-gamma-carboxyglutamic acid at 67 [ModifiedResidue:140882] L-gamma-carboxyglutamic acid at 66 [ModifiedResidue:140883] L-gamma-carboxyglutamic acid at 63 [ModifiedResidue:140884] L-gamma-carboxyglutamic acid at 61 [ModifiedResidue:140885] L-gamma-carboxyglutamic acid at 54 [ModifiedResidue:8865023] L-gamma-carboxyglutamic acid at 53 [ModifiedResidue:140818] (2S,3R)-3-hydroxyaspartic acid at 110
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-140886] 12xCbxE-3D-F9(47-461) [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-140886] 12xCbxE-3D-F9(47-461) [extracellular region] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-140886] F9 [extracellular region] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-140886] F9 [extracellular region] - Bos taurus [EntityWithAccessionedSequence:R-SSC-140886] F9 [extracellular region] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-140886] f9b [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-XTR-140886] f9 [extracellular region] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-140886] F9 [extracellular region] - Gallus gallus
literatureReference	[LiteratureReference:140887] Nucleotide sequence of the gene for human factor IX (antihemophilic factor B) [LiteratureReference:140890] The occurrence of beta-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens
maxDepth	1
modified	[InstanceEdit:8865022] D'Eustachio, Peter, 2016-03-17
name	12xCbxE-3D-F9(47-461) 12xCbxE-3D-F9 factor IX
producedByEvent	[BlackBoxEvent:R-HSA-9670673] FIX is secreted - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P00740] UniProt:P00740 F9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-140886
startCoordinate	47
updateTrackers	[UpdateTracker:9885970] Update Tracker - [EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] - v45:[addName] [UpdateTracker:9894346] Update Tracker - [EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] - v57:[addHasModifiedResidue, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9885970] Update Tracker - [EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] - v45:[addName] [UpdateTracker:9894346] Update Tracker - [EntityWithAccessionedSequence:140886] 12xCbxE-3D-F9(47-461) [extracellular region] - v57:[addHasModifiedResidue, modifyName]
(normalEntity)	[EntityFunctionalStatus:9673206] loss_of_function of F9 zymogen variant [extracellular region]
(input)	[Reaction:R-HSA-9936467] factor IX -> factor IXa + factor IX activation peptide (kallikrein catalyst) [Reaction:R-HSA-158333] factor IX -> factor IXa + factor IX activation peptide (factor XIa catalyst) [Reaction:R-HSA-9929051] TF:FVIIa+FIX -> TF:FVIIa:FIXa + FIX activation peptide (TF:F7a catalyst)
(output)	[BlackBoxEvent:R-HSA-9670673] FIX is secreted

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