Reactome | TIMM8:TIMM13 chaperones hydrophobic proteins

Schema > Reaction > Entries

TIMM8:TIMM13 chaperones hydrophobic proteins Show undefined attributes

authored	[InstanceEdit:1299477] May, B, 2011-05-21
category	binding
compartment	[Compartment:17927] mitochondrial intermembrane space
created	[InstanceEdit:1299483] May, B, 2011-05-23
dbId	1299484
displayName	TIMM8:TIMM13 chaperones hydrophobic proteins
edited	[InstanceEdit:1299477] May, B, 2011-05-21
eventOf	[Pathway:R-HSA-1268020] Mitochondrial protein import - Homo sapiens
followingEvent	[Reaction:R-HSA-1268025] SAM50 complex inserts proteins into mitochondrial outer membrane - Homo sapiens [Reaction:R-HSA-1307803] TIMM22 inserts proteins into inner membrane - Homo sapiens
inferredFrom	[Reaction:R-SCE-1252262] TIM8:TIM13 chaperones hydrophobic proteins - Saccharomyces cerevisiae
input	[CandidateSet:R-HSA-1299467] Proteins Chaperoned by TIMM8:TIMM13 [mitochondrial intermembrane space] [DefinedSet:R-HSA-1299461] TIMM8:TIMM13 [mitochondrial intermembrane space]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1299404] The calcium-binding aspartate/glutamate carriers, citrin and aralar1, are new substrates for the DDP1/TIMM8a-TIMM13 complex [LiteratureReference:1307738] Multiple pathways for mitochondrial protein traffic [LiteratureReference:1307739] Multiple pathways for sorting mitochondrial precursor proteins
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TIMM8:TIMM13 chaperones hydrophobic proteins
output	[Complex:R-HSA-1299471] TIMM8:TIMM13:Protein [mitochondrial intermembrane space]
precedingEvent	[Reaction:R-HSA-1268022] TOMM40 complex translocates proteins from the cytosol to the mitochondrial intermembrane space - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1914221] D'Eustachio, P, 2011-11-01 [InstanceEdit:2108993] Endo, T, 2012-02-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1299484
summation	[Summation:1307728] As inferred from the yeast TIM8:TIM13 complex, the human TIM...

Referrals

(hasEvent)	[Pathway:R-HSA-1268020] Mitochondrial protein import
(precedingEvent)	[Reaction:R-HSA-1268025] SAM50 complex inserts proteins into mitochondrial outer membrane [Reaction:R-HSA-1307803] TIMM22 inserts proteins into inner membrane
(inferredTo)	[Reaction:R-SCE-1252262] TIM8:TIM13 chaperones hydrophobic proteins

Cite Us!