Reactome | Homodimerization of ERBB4

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Homodimerization of ERBB4 Show undefined attributes

authored	[InstanceEdit:1972351] Orlic-Milacic, M, 2011-11-04 [InstanceEdit:9638819] Stern, David F, 2019-02-21
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:1250219] Orlic-Milacic, Marija, 2011-04-14
dbId	1250220
displayName	Homodimerization of ERBB4
edited	[InstanceEdit:1972361] Matthews, L, 2011-11-07 [InstanceEdit:9638824] Orlic-Milacic, Marija, 2019-03-05
eventOf	[Pathway:R-HSA-1236394] Signaling by ERBB4 - Homo sapiens
followingEvent	[Reaction:R-HSA-1250315] Trans-autophosphorylation of ERBB4 homodimers - Homo sapiens
input	2 × [DefinedSet:R-HSA-1236393] NRGs/EGF-like ligands:ERBB4 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1250222] Ligand discrimination in signaling through an ErbB4 receptor homodimer
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Homodimerization of ERBB4
orthologousEvent	[Reaction:R-DME-1250220] Homodimerization of ERBB4 - Drosophila melanogaster [Reaction:R-GGA-1250220] Homodimerization of ERBB4 - Gallus gallus [Reaction:R-XTR-1250220] Homodimerization of ERBB4 - Xenopus tropicalis [Reaction:R-DRE-1250220] Homodimerization of ERBB4 - Danio rerio [Reaction:R-SSC-1250220] Homodimerization of ERBB4 - Sus scrofa [Reaction:R-BTA-1250220] Homodimerization of ERBB4 - Bos taurus [Reaction:R-CFA-1250220] Homodimerization of ERBB4 - Canis familiaris [Reaction:R-RNO-1250220] Homodimerization of ERBB4 - Rattus norvegicus [Reaction:R-MMU-1250220] Homodimerization of ERBB4 - Mus musculus
output	[DefinedSet:R-HSA-1250221] ERBB4 homodimers [plasma membrane]
precedingEvent	[Reaction:R-HSA-1236398] ERBB4 binds NRGs or EGF-like ligands - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1979910] Harris, RC, 2011-11-11 [InstanceEdit:1979909] Zeng, F, 2011-11-11 [InstanceEdit:2104982] Earp HS, 3rd, 2012-02-20 [InstanceEdit:2104979] Misior, AM, 2012-02-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1250220
summation	[Summation:1250217] Ligand stimulated ERBB4 forms homodimers (Sweeney et al. 200...
updateTrackers	[UpdateTracker:9779626] Update Tracker - [Reaction:1250220] Homodimerization of ERBB4 - v65:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9779626] Update Tracker - [Reaction:1250220] Homodimerization of ERBB4 - v65:[modifyText]
(hasEvent)	[Pathway:R-HSA-1236394] Signaling by ERBB4
(precedingEvent)	[Reaction:R-HSA-1250315] Trans-autophosphorylation of ERBB4 homodimers