Reactome | Homodimerization of ERBB4

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Homodimerization of ERBB4 Show undefined attributes

category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10861337
displayName	Homodimerization of ERBB4
eventOf	[Pathway:R-DME-1236394] Signaling by ERBB4 - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DME-1250315] Trans-autophosphorylation of ERBB4 homodimers - Drosophila melanogaster
inferredFrom	[Reaction:R-HSA-1250220] Homodimerization of ERBB4 - Homo sapiens
input	2 × [DefinedSet:R-DME-1236393] NRGs/EGF-like ligands:ERBB4 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Homodimerization of ERBB4
output	[DefinedSet:R-DME-1250221] ERBB4 homodimers [plasma membrane]
precedingEvent	[Reaction:R-DME-1236398] ERBB4 binds NRGs or EGF-like ligands - Drosophila melanogaster
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:56210] Drosophila melanogaster
stId	R-DME-1250220
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-1236394] Signaling by ERBB4
(precedingEvent)	[Reaction:R-DME-1250315] Trans-autophosphorylation of ERBB4 homodimers
(inferredTo)	[Reaction:R-HSA-1250220] Homodimerization of ERBB4

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