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Schema
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Reaction
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Entries
PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins
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authored
[InstanceEdit:1183167] Jassal, B, 2011-02-10
catalystActivity
[CatalystActivity:1183105] protein-arginine deiminase activity of PADIs:Ca2+ [cytosol]
category
transition
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:1183167] Jassal, B, 2011-02-10
dbId
1183128
displayName
PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins
edited
[InstanceEdit:1183167] Jassal, B, 2011-02-10
eventOf
[Pathway:R-HSA-3247509] Chromatin modifying enzymes - Homo sapiens
input
[SimpleEntity:R-ALL-29356] H2O [cytosol]
[OtherEntity:R-ALL-1183111] Protein-L-arginine [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1183150] cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I
[LiteratureReference:1183134] Human peptidylarginine deiminase type II: molecular cloning, gene organization, and expression in human skin
[LiteratureReference:1183192] Human peptidylarginine deiminase type III: molecular cloning and nucleotide sequence of the cDNA, properties of the recombinant enzyme, and immunohistochemical localization in human skin
[LiteratureReference:1183149] Human PAD4 regulates histone arginine methylation levels via demethylimination
[LiteratureReference:1183110] Comparison of enzymatic properties between hPADI2 and hPADI4
[LiteratureReference:1183178] Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6
modified
[InstanceEdit:10560457] Wright, Adam, 2024-03-07
name
PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins
Protein citrullination
orthologousEvent
[Reaction:R-GGA-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Gallus gallus
[Reaction:R-XTR-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Xenopus tropicalis
[Reaction:R-SSC-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Sus scrofa
[Reaction:R-BTA-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Bos taurus
[Reaction:R-CFA-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Canis familiaris
[Reaction:R-RNO-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Rattus norvegicus
[Reaction:R-MMU-1183128] PADIs:Ca2+ deiminate L-Arg to L-Cit in proteins - Mus musculus
output
[SimpleEntity:R-ALL-29382] NH3 [cytosol]
[OtherEntity:R-ALL-1183191] Protein-L-citrulline [cytosol]
releaseDate
2016-03-23
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-1183128
summation
[Summation:1183122] Methylation of histones by protein arginine methyltransferas...
Referrals
(hasEvent)
[Pathway:R-HSA-3247509] Chromatin modifying enzymes
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