Reactome | Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:1169238] protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-1169188] SHP1 (PTPN6) dephosphorylates JAK2 - Homo sapiens
created	[InstanceEdit:1169244] Jupe, S, 2011-01-14
dbId	1169243
displayName	Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane]
hasComponent	[Complex:R-HSA-1168898] Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer [plasma membrane] [EntityWithAccessionedSequence:R-HSA-197938] PTPN6 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	false
maxDepth	5
name	Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1
producedByEvent	[Reaction:R-HSA-1168839] SHP1 (PTPN6) binds JAK2 in the receptor complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1169243

(input)	[Reaction:R-HSA-1169188] SHP1 (PTPN6) dephosphorylates JAK2
(physicalEntity)	[CatalystActivity:1169238] protein tyrosine phosphatase activity of Growth Hormone: Tyrosine phosphorylated Growth Hormone Receptor-p(Y1007)-JAK2 dimer:SHP1 [plasma membrane]
(output)	[Reaction:R-HSA-1168839] SHP1 (PTPN6) binds JAK2 in the receptor complex

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