Reactome | MPG glycosylase mediated recognition and binding of ethenoadenine

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MPG glycosylase mediated recognition and binding of ethenoadenine Show undefined attributes

authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
dbId	110239
displayName	MPG glycosylase mediated recognition and binding of ethenoadenine
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
eventOf	[Pathway:R-HSA-110330] Recognition and association of DNA glycosylase with site containing an affected purine - Homo sapiens
followingEvent	[Reaction:R-HSA-110250] Cleavage of ethenoadenine by MPG glycosylase - Homo sapiens
input	[GenomeEncodedEntity:R-HSA-110203] EtAD-dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-49155] MPG [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5634850] 1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase) [LiteratureReference:5634851] Escherichia coli, Saccharomyces cerevisiae, rat and human 3-methyladenine DNA glycosylases repair 1,N6-ethenoadenine when present in DNA
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	MPG glycosylase mediated recognition and binding of ethenoadenine
output	[Complex:R-HSA-110204] MPG:EtAD-dsDNA [nucleoplasm]
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-110239
summation	[Summation:178954] MPG, a 3-methyladenine DNA glycosylase, recognizes alkylatio...
updateTrackers	[UpdateTracker:9785888] Update Tracker - [Reaction:110239] MPG glycosylase mediated recognition and binding of ethenoadenine - v51:[addLiteratureReference, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785888] Update Tracker - [Reaction:110239] MPG glycosylase mediated recognition and binding of ethenoadenine - v51:[addLiteratureReference, modifyText]
(hasEvent)	[Pathway:R-HSA-110330] Recognition and association of DNA glycosylase with site containing an affected purine
(precedingEvent)	[Reaction:R-HSA-110250] Cleavage of ethenoadenine by MPG glycosylase

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