Reactome | Cleavage of thymine by TDG glycosylase

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Cleavage of thymine by TDG glycosylase Show undefined attributes

authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
catalystActivity	[CatalystActivity:5649479] DNA N-glycosylase activity of TDG:(T:G)-dsDNA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
dbId	110219
displayName	Cleavage of thymine by TDG glycosylase
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
eventOf	[Pathway:R-HSA-110329] Cleavage of the damaged pyrimidine - Homo sapiens
followingEvent	[Reaction:R-HSA-110350] Displacement of TDG glycosylase by APEX1 at the AP site - Homo sapiens
input	[Complex:R-HSA-110150] TDG:(T:G)-dsDNA [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5637477] The purification of a mismatch-specific thymine-DNA glycosylase from HeLa cells [LiteratureReference:5637479] Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase
maxDepth	1
modified	[InstanceEdit:11051501] Weiser, Joel, 2026-03-16
name	Cleavage of thymine by TDG glycosylase
orthologousEvent	[Reaction:R-SPO-110219] Cleavage of thymine by TDG glycosylase - Schizosaccharomyces pombe [Reaction:R-DME-110219] Cleavage of thymine by TDG glycosylase - Drosophila melanogaster [Reaction:R-GGA-110219] Cleavage of thymine by TDG glycosylase - Gallus gallus [Reaction:R-XTR-110219] Cleavage of thymine by TDG glycosylase - Xenopus tropicalis [Reaction:R-DRE-110219] Cleavage of thymine by TDG glycosylase - Danio rerio [Reaction:R-SSC-110219] Cleavage of thymine by TDG glycosylase - Sus scrofa [Reaction:R-BTA-110219] Cleavage of thymine by TDG glycosylase - Bos taurus [Reaction:R-CFA-110219] Cleavage of thymine by TDG glycosylase - Canis familiaris [Reaction:R-RNO-110219] Cleavage of thymine by TDG glycosylase - Rattus norvegicus [Reaction:R-MMU-110219] Cleavage of thymine by TDG glycosylase - Mus musculus
output	[Complex:R-HSA-110191] TDG:AP-dsDNA [nucleoplasm] [SimpleEntity:R-ALL-29692] Thy [nucleoplasm]
precedingEvent	[Reaction:R-HSA-110158] TDG glycosylase mediated recognition and binding of a thymine opposite to a guanine - Homo sapiens
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-110219
summation	[Summation:178538] TDG, a G/T mismatch-specific thymine DNA glycosylase, cleave...
updateTrackers	[UpdateTracker:9785646] Update Tracker - [Reaction:110219] Cleavage of thymine by TDG glycosylase - v51:[addLiteratureReference, modifyText] [UpdateTracker:9785230] Update Tracker - [Reaction:110219] Cleavage of thymine by TDG glycosylase - v52:[add_removeCatalystActivity, modifyText, removeLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9785646] Update Tracker - [Reaction:110219] Cleavage of thymine by TDG glycosylase - v51:[addLiteratureReference, modifyText] [UpdateTracker:9785230] Update Tracker - [Reaction:110219] Cleavage of thymine by TDG glycosylase - v52:[add_removeCatalystActivity, modifyText, removeLiteratureReference]
(precedingEvent)	[Reaction:R-HSA-110350] Displacement of TDG glycosylase by APEX1 at the AP site
(hasEvent)	[Pathway:R-HSA-110329] Cleavage of the damaged pyrimidine

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