Reactome | NTHL1 glycosylase mediated recognition and binding of cytosine glycol

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NTHL1 glycosylase mediated recognition and binding of cytosine glycol Show undefined attributes

authored	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
dbId	110208
diseaseReaction	[FailedReaction:R-HSA-9630047] Defective NTHL1 truncation mutants do not bind cytosine glycol (Cg) - Homo sapiens
displayName	NTHL1 glycosylase mediated recognition and binding of cytosine glycol
edited	[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00 [InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
eventOf	[Pathway:R-HSA-110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine - Homo sapiens
followingEvent	[Reaction:R-HSA-110226] Cleavage of cytosine glycol by NTHL1 glycosylase - Homo sapiens
input	[GenomeEncodedEntity:R-HSA-110178] Cg-dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-60537] NTHL1 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5637573] Excision of products of oxidative DNA base damage by human NTH1 protein
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NTHL1 glycosylase mediated recognition and binding of cytosine glycol
output	[Complex:R-HSA-110179] NTHL1:Cg-dsDNA [nucleoplasm]
releaseDate	2004-03-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5673689] Borowiec, James, 2014-12-22
revised	[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-110208
summation	[Summation:178864] NTHL1 (hNTH1; endonuclease III-like protein 1) recognizes an...
updateTrackers	[UpdateTracker:9785886] Update Tracker - [Reaction:110208] NTHL1 glycosylase mediated recognition and binding of cytosine glycol - v51:[addLiteratureReference, modifyText] [UpdateTracker:9785090] Update Tracker - [Reaction:110208] NTHL1 glycosylase mediated recognition and binding of cytosine glycol - v52:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9785886] Update Tracker - [Reaction:110208] NTHL1 glycosylase mediated recognition and binding of cytosine glycol - v51:[addLiteratureReference, modifyText] [UpdateTracker:9785090] Update Tracker - [Reaction:110208] NTHL1 glycosylase mediated recognition and binding of cytosine glycol - v52:[modifyText]
(normalReaction)	[FailedReaction:R-HSA-9630047] Defective NTHL1 truncation mutants do not bind cytosine glycol (Cg)
(hasEvent)	[Pathway:R-HSA-110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine
(precedingEvent)	[Reaction:R-HSA-110226] Cleavage of cytosine glycol by NTHL1 glycosylase

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