Reactome | OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]

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OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] Show undefined attributes

catalystActivities	[CatalystActivity:5643997] oxidized purine nucleobase lesion DNA N-glycosylase activity of OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-110243] Excision of 8-oxoguanine by OGG1 glycosylase - Homo sapiens
created	[InstanceEdit:110175] Matthews, L, 2004-01-29 08:00:00
dbId	110185
displayName	OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-HSA-110184] (8oxoG:Cyt)-dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-60887] OGG1 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Mus musculus [Complex:R-RNO-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Canis familiaris [Complex:R-BTA-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Bos taurus [Complex:R-DRE-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Danio rerio [Complex:R-XTR-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Gallus gallus [Complex:R-DME-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Drosophila melanogaster [Complex:R-DDI-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Dictyostelium discoideum [Complex:R-SCE-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Saccharomyces cerevisiae [Complex:R-PFA-110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - Plasmodium falciparum
maxDepth	2
modified	[InstanceEdit:9663830] Orlic-Milacic, Marija, 2019-10-15
name	OGG1:(8oxoG:Cyt)-dsDNA OGG1:8-oxo guanine complex
producedByEvent	[Reaction:R-HSA-110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-110185
updateTrackers	[UpdateTracker:9900909] Update Tracker - [Complex:110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - v71:[modifyName] [UpdateTracker:9889975] Update Tracker - [Complex:110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - v52:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9900909] Update Tracker - [Complex:110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - v71:[modifyName] [UpdateTracker:9889975] Update Tracker - [Complex:110185] OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm] - v52:[modifyName]
(normalEntity)	[EntityFunctionalStatus:9656302] loss_of_function of OGG1 mutants:(8oxoG:Cyt)-dsDNA [nucleoplasm]
(output)	[Reaction:R-HSA-110235] OGG1 glycosylase mediated recognition and binding of an 8-oxoguanine opposite to a cytosine
(input)	[Reaction:R-HSA-110243] Excision of 8-oxoguanine by OGG1 glycosylase
(physicalEntity)	[CatalystActivity:5643997] oxidized purine nucleobase lesion DNA N-glycosylase activity of OGG1:(8oxoG:Cyt)-dsDNA [nucleoplasm]

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