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Schema
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Reaction
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Entries
MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences
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authored
[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
category
binding
compartment
[Compartment:7660] nucleoplasm
created
[InstanceEdit:110148] Matthews, L, 2004-01-28 20:00:00
dbId
110171
displayName
MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences
edited
[InstanceEdit:110568] Matthews, L, 2004-02-03 00:30:00
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
eventOf
[Pathway:R-HSA-110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine - Homo sapiens
followingEvent
[Reaction:R-HSA-110231] Cleavage of uracil by MBD4 glycosylase - Homo sapiens
input
[GenomeEncodedEntity:R-HSA-110167] CpG(U:G)-dsDNA [nucleoplasm]
[EntityWithAccessionedSequence:R-HSA-3006633] MBD4 [nucleoplasm]
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:5637552] Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain
maxDepth
1
modified
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences
output
[Complex:R-HSA-110168] MBD4:CpG(U:G)-dsDNA [nucleoplasm]
releaseDate
2004-03-06
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:5673689] Borowiec, James, 2014-12-22
revised
[InstanceEdit:5654671] Orlic-Milacic, Marija, 2014-12-03
schemaClass
Reaction
species
[Species:48887] Homo sapiens
stId
R-HSA-110171
summation
[Summation:178947] MBD4 (MED1; methyl-CpG-binding domain protein 4) recognizes ...
updateTrackers
[UpdateTracker:9785662] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v51:[addLiteratureReference, modifyText]
[UpdateTracker:9787560] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v44:[add_removeInput]
[UpdateTracker:9785179] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v52:[modifyText]
Referrals
(updatedInstance)
[UpdateTracker:9785662] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v51:[addLiteratureReference, modifyText]
[UpdateTracker:9787560] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v44:[add_removeInput]
[UpdateTracker:9785179] Update Tracker - [Reaction:110171] MBD4 glycosylase mediated recognition and binding of an uracil opposite to a guanine at CpG sequences - v52:[modifyText]
(hasEvent)
[Pathway:R-HSA-110328] Recognition and association of DNA glycosylase with site containing an affected pyrimidine
(precedingEvent)
[Reaction:R-HSA-110231] Cleavage of uracil by MBD4 glycosylase
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