Reactome | Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA

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Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA Show undefined attributes

catalystActivity	[CatalystActivity:109984] delta(3)-delta(2)-enoyl-CoA isomerase activity of DCI dimer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:109340] Gillespie, ME, 2004-01-02 00:00:00
dbId	109338
displayName	Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA
eventOf	[Pathway:R-HSA-77288] mitochondrial fatty acid beta-oxidation of unsaturated fatty acids - Homo sapiens
figure	[Figure:109985] /figures/unsatfattyacidbetao_2.jpg
followingEvent	[BlackBoxEvent:R-HSA-109342] Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation - Homo sapiens
input	[SimpleEntity:R-ALL-77358] cis,cis-3,6-Dodecadienoyl-CoA [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[Book:77402] The Metabolic and Molecular Bases of Inherited Disease, 8th ed Scriver, CR Mitochondrial fatty acid oxidation disorders 0079130356
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA
orthologousEvent	[Reaction:R-DME-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Drosophila melanogaster [Reaction:R-GGA-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Gallus gallus [Reaction:R-XTR-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Xenopus tropicalis [Reaction:R-SSC-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Sus scrofa [Reaction:R-BTA-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Bos taurus [Reaction:R-CFA-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Canis familiaris [Reaction:R-RNO-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Rattus norvegicus [Reaction:R-MMU-109338] Isomerization of cis,cis-3,6-Dodecadienoyl-CoA to form trans,cis-Lauro-2,6-dienoyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-77360] trans,cis-Lauro-2,6-dienoyl-CoA [mitochondrial matrix]
precedingEvent	[BlackBoxEvent:R-HSA-109339] Linoleoyl-CoA is converted to cis,cis-3,6- dodecadienoyl-CoA by three cycles of beta-oxidation - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-109338
summation	[Summation:178921] At the beginning of this reaction, 1 molecule of 'cis,cis-3,...

Referrals

(hasEvent)	[Pathway:R-HSA-77288] mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
(precedingEvent)	[BlackBoxEvent:R-HSA-109342] Trans,cis-lauro-2,6-dienoyl-CoA is converted to cis,cis-3,6- 4-cis-decenoyl-CoA by one cycle of beta-oxidation