Reactome | IL6:IL6R-2:IL6ST-2 [extracellular region]

Schema > Complex > Entries

IL6:IL6R-2:IL6ST-2 [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:1067679] Jupe, S, 2010-11-26
dbId	1067674
displayName	IL6:IL6R-2:IL6ST-2 [extracellular region]
hasComponent	[Complex:R-HSA-1067687] IL6:IL6R-2 [extracellular region] [EntityWithAccessionedSequence:R-HSA-1067653] IL6ST-2 [extracellular region]
inDisease	false
inferredTo	[Complex:R-MMU-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Mus musculus [Complex:R-RNO-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Rattus norvegicus [Complex:R-CFA-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Canis familiaris [Complex:R-BTA-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Bos taurus [Complex:R-SSC-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Sus scrofa [Complex:R-DRE-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Danio rerio [Complex:R-XTR-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Xenopus tropicalis [Complex:R-GGA-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Gallus gallus
isChimeric	false
maxDepth	3
modified	[InstanceEdit:8963884] Jupe, Steve, 2017-02-13
name	IL6:IL6R-2:IL6ST-2 IL6:sIL6R:sgp130
negativelyRegulates	[NegativeRegulation:R-HSA-1164957] Negative regulation by 'IL6:IL6R-2:IL6ST-2 [extracellular region]'
producedByEvent	[Reaction:R-HSA-1067676] IL6:IL6R-2 binds IL6ST-2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1067674
updateTrackers	[UpdateTracker:9896313] Update Tracker - [Complex:1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - v60:[addName, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9896313] Update Tracker - [Complex:1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - v60:[addName, updateContainedComponent]
(output)	[Reaction:R-HSA-1067676] IL6:IL6R-2 binds IL6ST-2
(regulator)	[NegativeRegulation:R-HSA-1164957] Negative regulation by 'IL6:IL6R-2:IL6ST-2 [extracellular region]'

© 2026 Reactome

Cite Us!