Reactome | IL6:IL6R-2:IL6ST-2 [extracellular region]

Schema > Complex > Entries

compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10374644
displayName	IL6:IL6R-2:IL6ST-2 [extracellular region]
hasComponent	[Complex:R-BTA-1067687] IL6:IL6R-2 [extracellular region] [EntityWithAccessionedSequence:R-BTA-1067653] IL6ST [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region] - Homo sapiens
maxDepth	3
name	IL6:IL6R-2:IL6ST-2
negativelyRegulates	[NegativeRegulation:10374647] Negative regulation by 'IL6:IL6R-2:IL6ST-2 [extracellular region]'
producedByEvent	[Reaction:R-BTA-1067676] IL6:IL6R-2 binds IL6ST-2 - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-1067674
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-1067676] IL6:IL6R-2 binds IL6ST-2
(regulator)	[NegativeRegulation:10374647] Negative regulation by 'IL6:IL6R-2:IL6ST-2 [extracellular region]'
(inferredTo)	[Complex:R-HSA-1067674] IL6:IL6R-2:IL6ST-2 [extracellular region]

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