Reactome | ?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+

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?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+ Show undefined attributes

catalystActivity	[CatalystActivity:10823049] protein-glutamine gamma-glutamyltransferase activity of factor XIIIa [extracellular region]
category	omitted
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10823051
displayName	?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+
eventOf	[Pathway:R-GGA-9769733] Fibrin formation - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9921091] ?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+ - Homo sapiens
input	[Complex:R-GGA-114559] Integrin alpha IIb beta 3:fibrin multimer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+ ITGA2B:ITGB3:fibrin multimer ->ITGA2B:ITGB3:fibrin multimer, crosslinked + NH4+
output	[SimpleEntity:R-ALL-140912] NH4+ [extracellular region] [Complex:R-GGA-9933756] ?IIb?3:fibrin multimer, crosslinked [plasma membrane]
precedingEvent	[Reaction:R-GGA-140847] factor XIII cleaved tetramer + 2 Ca++ -> factor XIIIa + 2 factor XIII B chain - Gallus gallus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:49591] Gallus gallus
stId	R-GGA-9921091
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9769733] Fibrin formation
(inferredTo)	[BlackBoxEvent:R-HSA-9921091] ?IIb?3:fibrin multimer ->?IIb?3:fibrin multimer, crosslinked + NH4+

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