Reactome | MAPK1 phosphorylates SOX10

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MAPK1 phosphorylates SOX10 Show undefined attributes

catalystActivity	[CatalystActivity:10778327] protein serine/threonine kinase activity of p-T,Y MAPK dimers [cytosol]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10820519
displayName	MAPK1 phosphorylates SOX10
eventOf	[Pathway:R-GGA-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9824582] MAPK1 phosphorylates SOX10 - Homo sapiens
input	2 × [SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-9613639] SOX10 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPK1 phosphorylates SOX10
output	2 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-9824578] phospho-SOX10 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9824582
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity
(inferredTo)	[Reaction:R-HSA-9824582] MAPK1 phosphorylates SOX10