Reactome | activated TLR homodimer : MyD88 complex [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-GGA-433838] IRAK4 : MyD88 : activated TLR5 or TLR15 [plasma membrane] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-434130] IRAK4 binds to activated TLR5 or 15 - Gallus gallus
created	[InstanceEdit:977249] Shamovsky, V, 2010-10-15
dbId	977241
displayName	activated TLR homodimer : MyD88 complex [plasma membrane]
hasComponent	[DefinedSet:R-GGA-977246] activated TLR5 or 15 bound to ligand [plasma membrane] 2 × [EntityWithAccessionedSequence:R-GGA-433900] MyD88 [plasma membrane]
inDisease	false
maxDepth	5
modified	[InstanceEdit:8959586] Weiser, JD
name	activated TLR homodimer : MyD88 complex
producedByEvent	[Reaction:R-GGA-977238] Activated TLR5/TLR15 homodimer recruits MyD88 adaptor - Gallus gallus
relatedSpecies	[Species:451465] Salmonella typhimurium
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-977241
updateTrackers	[UpdateTracker:9892762] Update Tracker - [Complex:977241] activated TLR homodimer : MyD88 complex [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9895978] Update Tracker - [Complex:977241] activated TLR homodimer : MyD88 complex [plasma membrane] - v60:[removeSpecies, updateContainedComponent]

(updatedInstance)	[UpdateTracker:9892762] Update Tracker - [Complex:977241] activated TLR homodimer : MyD88 complex [plasma membrane] - v54:[updateContainedComponent] [UpdateTracker:9895978] Update Tracker - [Complex:977241] activated TLR homodimer : MyD88 complex [plasma membrane] - v60:[removeSpecies, updateContainedComponent]
(output)	[Reaction:R-GGA-977238] Activated TLR5/TLR15 homodimer recruits MyD88 adaptor
(input)	[Reaction:R-GGA-434130] IRAK4 binds to activated TLR5 or 15
(hasComponent)	[Complex:R-GGA-433838] IRAK4 : MyD88 : activated TLR5 or TLR15 [plasma membrane] [Complex:R-GGA-977234] activated TLR : MyD88 : p-IRAK4 [plasma membrane]