Reactome | Negative Regulation of CDH1 Gene Transcription

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Negative Regulation of CDH1 Gene Transcription Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828417
displayName	Negative Regulation of CDH1 Gene Transcription
eventOf	[Pathway:R-GGA-9764560] Regulation of CDH1 Gene Transcription - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-9764826] DNTTIP1 recruits KDM1A to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9764932] PRC2 (EZH2) core complex methylates nucleosomes at CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9765788] TWIST1 recruits SETD8 to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9764786] ZEB1 recruits SMARCA4 to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9930711] ZEB1 recruits TLE1 and HDAC1/2 to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9765791] ZEB1 recruits SETD8 to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9765850] ZEB1 recruits MPHOSPH8 (MPP8) to CDH1 gene promoter - Gallus gallus [Reaction:R-GGA-9765973] CTBP1,CTBP2 binds ZEB1 - Gallus gallus
inferredFrom	[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Negative Regulation of CDH1 Gene Transcription
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-9764725
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9764560] Regulation of CDH1 Gene Transcription
(inferredTo)	[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription

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