Reactome | mature p21 RAS binds GDP

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mature p21 RAS binds GDP Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10817137
displayName	mature p21 RAS binds GDP
eventOf	[Pathway:R-GGA-9648002] RAS processing - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9649735] Intrinsic nucleotide exchange on RAS - Gallus gallus
inferredFrom	[Reaction:R-HSA-9649733] mature p21 RAS binds GDP - Homo sapiens
input	[SimpleEntity:R-ALL-29420] GDP [cytosol] [DefinedSet:R-GGA-9649715] mature p21 RAS [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	mature p21 RAS binds GDP
output	[Complex:R-GGA-109796] p21 RAS:GDP [plasma membrane]
precedingEvent	[BlackBoxEvent:R-GGA-9647980] mature RAS proteins translocate to plasma membrane - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9649733
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-9648002] RAS processing
(precedingEvent)	[Reaction:R-GGA-9649735] Intrinsic nucleotide exchange on RAS
(inferredTo)	[Reaction:R-HSA-9649733] mature p21 RAS binds GDP

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