Reactome | GRB2:GAB2 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-914021] High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] - Gallus gallus
consumedByEvent	[BlackBoxEvent:R-GGA-453104] Phosphorylated SHC1 recruits GRB2:GAB2 - Gallus gallus [BlackBoxEvent:R-GGA-453104] Phosphorylated SHC1 recruits GRB2:GAB2 - Gallus gallus [BlackBoxEvent:R-GGA-453104] Phosphorylated SHC1 recruits GRB2:GAB2 - Gallus gallus [BlackBoxEvent:R-GGA-453104] Phosphorylated SHC1 recruits GRB2:GAB2 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10761180
displayName	GRB2:GAB2 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-GGA-508239] GAB2 [cytosol] [EntityWithAccessionedSequence:R-GGA-74686] GRB2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-912522] GRB2:GAB2 [cytosol] - Homo sapiens
maxDepth	2
name	GRB2:GAB2
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-912522
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[BlackBoxEvent:R-GGA-453104] Phosphorylated SHC1 recruits GRB2:GAB2
(hasComponent)	[Complex:R-GGA-914021] High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] [Complex:R-GGA-912538] IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] [Complex:R-GGA-914047] High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:GAB2 [plasma membrane] [Complex:R-GGA-508246] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:GAB2 [plasma membrane]
(inferredTo)	[Complex:R-HSA-912522] GRB2:GAB2 [cytosol]

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