Reactome | MPST transfers sulfur atom from 3MPYR to form CysS248-MPST

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MPST transfers sulfur atom from 3MPYR to form CysS248-MPST Show undefined attributes

catalystActivity	[CatalystActivity:10814270] sulfurtransferase activity of MPST [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10815784
displayName	MPST transfers sulfur atom from 3MPYR to form CysS248-MPST
eventOf	[Pathway:R-GGA-1614558] Degradation of cysteine and homocysteine - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Gallus gallus
inferredFrom	[Reaction:R-HSA-9034756] MPST transfers sulfur atom from 3MPYR to form CysS248-MPST - Homo sapiens
input	[SimpleEntity:R-ALL-9012592] 3MPYR [mitochondrial matrix] [EntityWithAccessionedSequence:R-GGA-9012720] MPST [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	MPST transfers sulfur atom from 3MPYR to form CysS248-MPST L-cysteinyl-(protein) => pyruvate + S-sulfanyl-L-cysteinyl-(protein)
output	[EntityWithAccessionedSequence:R-GGA-9034913] MPST [mitochondrial matrix] [SimpleEntity:R-ALL-113557] PYR [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-9034756
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-1614558] Degradation of cysteine and homocysteine
(precedingEvent)	[Reaction:R-GGA-9035484] MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST
(inferredTo)	[Reaction:R-HSA-9034756] MPST transfers sulfur atom from 3MPYR to form CysS248-MPST

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