Reactome | G beta:gamma signalling through CDC42

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G beta:gamma signalling through CDC42 Show undefined attributes

compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10828179
displayName	G beta:gamma signalling through CDC42
eventOf	[Pathway:R-GGA-397795] G-protein beta:gamma signalling - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-8964619] PAK1 binds ARHGEF6 - Gallus gallus [Reaction:R-GGA-8964605] PAK1:ARHGEF6 complex binds G-protein beta-gamma complex - Gallus gallus [Reaction:R-GGA-8964634] CDC42 binds GNB/GNG:PAK1:ARHGEF6 complex - Gallus gallus [Reaction:R-GGA-8964604] CDC42 in GNB/GNG:PAK1:ARHGEF6:CDC42 is activated - Gallus gallus [Reaction:R-GGA-8964614] PAK1 in GNB/GNG:PAK1:ARHGEF6:Active CDC42 is activated - Gallus gallus [Reaction:R-GGA-8964599] Active PAK1 and Active CDC42 dissociates from GNB/GNG:PAK1:ARHGEF6:CDC42 complex - Gallus gallus
inferredFrom	[Pathway:R-HSA-8964616] G beta:gamma signalling through CDC42 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	G beta:gamma signalling through CDC42
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-8964616
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-397795] G-protein beta:gamma signalling
(inferredTo)	[Pathway:R-HSA-8964616] G beta:gamma signalling through CDC42

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