Reactome | Clusterin binds C5b-C7, C8, C9

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10805808
displayName	Clusterin binds C5b-C7, C8, C9
eventOf	[Pathway:R-GGA-977606] Regulation of Complement cascade - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8852580] Clusterin binds C5b-C7, C8, C9 - Homo sapiens
input	[DefinedSet:R-GGA-8852568] C5b:C6:C7, C8, C9 [extracellular region] [Complex:R-GGA-6810665] CLU [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Clusterin binds C5b-C7, C8, C9
output	[Complex:R-GGA-8852569] CLU:C5b:C6:C7, C8, C9 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-8852580
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-977606] Regulation of Complement cascade
(inferredTo)	[Reaction:R-HSA-8852580] Clusterin binds C5b-C7, C8, C9

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