Reactome | glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2

Schema > Reaction > Entries

glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 Show undefined attributes

catalystActivity	[CatalystActivity:10734149] glutaryl-CoA dehydrogenase activity of GCDH tetramer [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10734151
displayName	glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2
eventOf	[Pathway:R-GGA-71064] Lysine catabolism - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-77314] Crotonoyl-CoA+H2O => (S)-3-Hydroxybutanoyl-CoA - Gallus gallus
inferredFrom	[Reaction:R-HSA-71046] glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 - Homo sapiens
input	[SimpleEntity:R-ALL-113596] FAD [mitochondrial matrix] [SimpleEntity:R-ALL-70955] GL-CoA [mitochondrial matrix] 2 × [SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix]
isInDisease	false
isInferred	true
maxDepth	1
name	glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2 FAD + glutaryl-CoA + 2 H(+) => (2E)-butenoyl-CoA + CO2 + FADH2
output	[SimpleEntity:R-ALL-29376] CO2 [mitochondrial matrix] [SimpleEntity:R-ALL-71045] crotonyl-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-31649] FADH2 [mitochondrial matrix]
precedingEvent	[Reaction:R-GGA-9858590] DLST transfers glutaryl to CoA - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-71046
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-71064] Lysine catabolism
(precedingEvent)	[Reaction:R-GGA-77314] Crotonoyl-CoA+H2O => (S)-3-Hydroxybutanoyl-CoA
(inferredTo)	[Reaction:R-HSA-71046] glutaryl-CoA + FAD => crotonyl-CoA + FADH2 + CO2

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