Reactome | Loading of PCNA - Sliding Clamp Formation

Schema > Reaction > Entries

Loading of PCNA - Sliding Clamp Formation Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10732960
displayName	Loading of PCNA - Sliding Clamp Formation
eventOf	[Pathway:R-GGA-69091] Polymerase switching - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-69068] RFC dissociates after sliding clamp formation - Gallus gallus
inferredFrom	[Reaction:R-HSA-69063] Loading of PCNA - Sliding Clamp Formation - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-GGA-68440] PCNA homotrimer [nucleoplasm] [Complex:R-GGA-68437] RFC Heteropentamer:RNA primer-DNA primer:origin duplex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Loading of PCNA - Sliding Clamp Formation
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-GGA-68471] RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm]
precedingEvent	[Reaction:R-GGA-69053] RFC binding displaces Pol Alpha - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-69063
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-69091] Polymerase switching
(precedingEvent)	[Reaction:R-GGA-69068] RFC dissociates after sliding clamp formation
(inferredTo)	[Reaction:R-HSA-69063] Loading of PCNA - Sliding Clamp Formation

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