Reactome | FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10798821] protein serine/threonine kinase activity of FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-GGA-6788392] ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10798818
displayName	FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]
hasComponent	[Complex:R-GGA-176269] ATR:ATRIP [nucleoplasm] [Complex:R-GGA-6785340] FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA [nucleoplasm] [Complex:R-GGA-68462] RPA heterotrimer [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-6788386] FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm] - Homo sapiens
maxDepth	7
name	FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP
producedByEvent	[Reaction:R-GGA-6788385] The complex of ATR and ATRIP is recruited to ICL-DNA - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-6788386
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-6788392] ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
(physicalEntity)	[CatalystActivity:10798821] protein serine/threonine kinase activity of FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]
(output)	[Reaction:R-GGA-6788385] The complex of ATR and ATRIP is recruited to ICL-DNA
(inferredTo)	[Complex:R-HSA-6788386] FANCD2:FANCI:UBE2T:FA Core Complex:ICL-DNA:RPA:ATR:ATRIP [nucleoplasm]

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