Reactome | HDR through Single Strand Annealing (SSA)

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HDR through Single Strand Annealing (SSA) Show undefined attributes

created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10825459
displayName	HDR through Single Strand Annealing (SSA)
eventOf	[Pathway:R-GGA-5693567] HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-75998] Formation of RAD52 heptameric ring structure complexes - Gallus gallus [Reaction:R-GGA-5686587] ABL1 phosphorylates RAD52 - Gallus gallus [Reaction:R-GGA-5693580] Association of RAD52 with the RPA complex at resected DNA DSBs - Gallus gallus [Reaction:R-GGA-5693564] Association of RAD51 with RAD52:DNA double-strand break ends - Gallus gallus [Reaction:R-GGA-5686642] RAD52 promotes single strand annealing at resected DNA DSBs - Gallus gallus [Reaction:R-GGA-5686657] ERCC1:XPF cleaves flaps generated by SSA - Gallus gallus [BlackBoxEvent:R-GGA-9980021] LIG1 binds SSA sites - Gallus gallus
inferredFrom	[Pathway:R-HSA-5685938] HDR through Single Strand Annealing (SSA) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	HDR through Single Strand Annealing (SSA)
precedingEvent	[Pathway:R-GGA-5693607] Processing of DNA double-strand break ends - Gallus gallus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-5685938
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5693567] HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
(inferredTo)	[Pathway:R-HSA-5685938] HDR through Single Strand Annealing (SSA)

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