Reactome | p-RPA heterotrimer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-9980018] p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10794728
displayName	p-RPA heterotrimer [nucleoplasm]
hasComponent	[DefinedSet:R-GGA-68461-3] Homologues of RPA1 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-5685148] phospho-RPA2 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-68459] RPA3 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5685169] p-RPA heterotrimer [nucleoplasm] - Homo sapiens
maxDepth	3
name	p-RPA heterotrimer
producedByEvent	[Reaction:R-GGA-6788392] ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-5685169
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-GGA-6788392] ATR phosphorylates RPA2, FANCI, FANCD2 and FANCM at ICL-DNA
(hasComponent)	[Complex:R-GGA-9980018] p-RPA:SSB-dsDNA with inter-SSA deletion:Flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] [Complex:R-GGA-5686615] p-RPA:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm] [Complex:R-GGA-5685161] p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5685169] p-RPA heterotrimer [nucleoplasm]