Reactome | POFUT2 transfers fucose to TSR domain-containing proteins

Schema > Reaction > Entries

POFUT2 transfers fucose to TSR domain-containing proteins Show undefined attributes

catalystActivity	[CatalystActivity:10788095] peptide-O-fucosyltransferase activity of POFUT2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10788097
displayName	POFUT2 transfers fucose to TSR domain-containing proteins
eventOf	[Pathway:R-GGA-5173214] O-glycosylation of TSR domain-containing proteins - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-5173005] B3GALTL transfers glucose to O-fucosyl-proteins - Gallus gallus
inferredFrom	[Reaction:R-HSA-5173192] POFUT2 transfers fucose to TSR domain-containing proteins - Homo sapiens
input	[SimpleEntity:R-ALL-1463452] GDP-Fuc [endoplasmic reticulum lumen] [CandidateSet:R-GGA-5173014] POFUT2 substrates [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	POFUT2 transfers fucose to TSR domain-containing proteins
output	[SimpleEntity:R-ALL-9942379] GDP [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-156540] H+ [endoplasmic reticulum lumen] [CandidateSet:R-GGA-5173164] O-fuc-proteins [endoplasmic reticulum lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-5173192
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-5173214] O-glycosylation of TSR domain-containing proteins
(precedingEvent)	[Reaction:R-GGA-5173005] B3GALTL transfers glucose to O-fucosyl-proteins
(inferredTo)	[Reaction:R-HSA-5173192] POFUT2 transfers fucose to TSR domain-containing proteins

Cite Us!