Reactome | BIRC8 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

BIRC8 [cytosol] Show undefined attributes

candidateOf	[CandidateSet:R-GGA-9967924] (RAC1 E3 ubiquitin ligases) [cytosol] - Gallus gallus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-114308] XIAP:Caspase-7 [cytosol] - Gallus gallus [Complex:R-GGA-114308] XIAP:Caspase-7 [cytosol] - Gallus gallus [Complex:R-GGA-9627441] SEPT4 dimer:XIAP [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-9627369] SEPT4 binds XIAP - Gallus gallus [Reaction:R-GGA-9627104] XIAP binds CASP3 - Gallus gallus [Reaction:R-GGA-9627104] XIAP binds CASP3 - Gallus gallus [Reaction:R-GGA-9627107] XIAP binds CASP7 - Gallus gallus [Reaction:R-GGA-9627107] XIAP binds CASP7 - Gallus gallus [Reaction:R-GGA-9627078] XIAP binds CASP9 - Gallus gallus [Reaction:R-GGA-9627078] XIAP binds CASP9 - Gallus gallus [Reaction:R-GGA-9627350] SMAC (DIABLO) binds XIAP - Gallus gallus [Reaction:R-GGA-9627350] SMAC (DIABLO) binds XIAP - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10739111
displayName	BIRC8 [cytosol]
endCoordinate	497
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-114444] XIAP [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-50849] XIAP [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-GGA-6807286] NEDD4,STUB1,WWP2 and XIAP [cytosol] - Gallus gallus
name	BIRC8 XIAP A0A8V0YRF2
negativelyRegulates	[NegativeRegulation:10739114] Negative regulation by 'XIAP [cytosol]'
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8V0YRF2] UniProt:A0A8V0YRF2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-50849
startCoordinate	1

Referrals

(hasCandidate)	[CandidateSet:R-GGA-9967924] (RAC1 E3 ubiquitin ligases) [cytosol] [CandidateSet:R-GGA-9967952] (CDC42 E3 ubiquitin ligases) [cytosol] [CandidateSet:R-GGA-6807260] XIAP,NEDD4 [cytosol] [CandidateSet:R-GGA-5357900] BIRC2,3,4 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-114444] XIAP [cytosol] [EntityWithAccessionedSequence:R-HSA-50849] XIAP [cytosol]
(hasMember)	[DefinedSet:R-GGA-6807286] NEDD4,STUB1,WWP2 and XIAP [cytosol]
(input)	[Reaction:R-GGA-9627369] SEPT4 binds XIAP [Reaction:R-GGA-9627350] SMAC (DIABLO) binds XIAP [Reaction:R-GGA-9627104] XIAP binds CASP3 [Reaction:R-GGA-9627107] XIAP binds CASP7 [Reaction:R-GGA-9627078] XIAP binds CASP9
(hasComponent)	[Complex:R-GGA-9627441] SEPT4 dimer:XIAP [cytosol] [Complex:R-GGA-9627066] XIAP:apoptosome [cytosol] [Complex:R-GGA-114308] XIAP:Caspase-7 [cytosol] [Complex:R-GGA-9627391] DIABLO dimer:XIAP [cytosol] [Complex:R-GGA-114304] XIAP:Caspase-3 [cytosol]
(regulator)	[NegativeRegulation:10739114] Negative regulation by 'XIAP [cytosol]'