Reactome | SRC-1 phosphorylates SHB

Schema > Reaction > Entries

SRC-1 phosphorylates SHB Show undefined attributes

catalystActivity	[CatalystActivity:10753219] protein tyrosine kinase activity of SRC-1 [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10786991
displayName	SRC-1 phosphorylates SHB
eventOf	[Pathway:R-GGA-4420097] VEGFA-VEGFR2 Pathway - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-4420128] SRC-1 phosphorylates SHB - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-GGA-4420196] VEGFA dimer:p-6Y-VEGFR2 dimer:SHB [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	SRC-1 phosphorylates SHB
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-GGA-4420164] VEGFA dimer:p-6Y-VEGFR2 dimer:p-S-SHB [plasma membrane]
precedingEvent	[Reaction:R-GGA-4420099] p-6Y-VEGFR2 binds SHB - Gallus gallus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-4420128
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-4420097] VEGFA-VEGFR2 Pathway
(inferredTo)	[Reaction:R-HSA-4420128] SRC-1 phosphorylates SHB

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