Reactome | Glypican-1 (GPC1) binds SLIT2

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10758459
displayName	Glypican-1 (GPC1) binds SLIT2
eventOf	[Pathway:R-GGA-376176] Signaling by ROBO receptors - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-428518] Glypican-1 (GPC1) binds SLIT2 - Homo sapiens
input	[Complex:R-GGA-428493] GPC1:HSPG [plasma membrane] [EntityWithAccessionedSequence:R-GGA-375997] SLIT2 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Glypican-1 (GPC1) binds SLIT2
output	[Complex:R-GGA-428489] SLIT2,SLIT2 cleavage fragments:GPC1:HSPG [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-428518
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-376176] Signaling by ROBO receptors
(inferredTo)	[Reaction:R-HSA-428518] Glypican-1 (GPC1) binds SLIT2

Cite Us!