Reactome | NoRC negatively regulates rRNA expression

Schema > Pathway > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10826845
displayName	NoRC negatively regulates rRNA expression
eventOf	[Pathway:R-GGA-5250941] Negative epigenetic regulation of rRNA expression - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21778] rDNA heterochromatin formation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-GGA-427337] MBD2 binds methylcytosine in chromatin - Gallus gallus
inferredFrom	[Pathway:R-HSA-427413] NoRC negatively regulates rRNA expression - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	NoRC negatively regulates rRNA expression Methylation of histones and DNA negatively regulates rRNA expression
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-427413
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-5250941] Negative epigenetic regulation of rRNA expression
(inferredTo)	[Pathway:R-HSA-427413] NoRC negatively regulates rRNA expression

Cite Us!