Reactome | hypoxanthine + H2O + NAD+ => xanthine + NADH + H+

Schema > Reaction > Entries

hypoxanthine + H2O + NAD+ => xanthine + NADH + H+ Show undefined attributes

authored	[InstanceEdit:421184] D'Eustachio, P, 2009-05-15 18:32:58
catalystActivity	[CatalystActivity:422402] hypoxanthine dehydrogenase activity of XDH [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:421176] D'Eustachio, P, 2009-05-15 18:35:38
dbId	421161
displayName	hypoxanthine + H2O + NAD+ => xanthine + NADH + H+
edited	[InstanceEdit:421184] D'Eustachio, P, 2009-05-15 18:32:58
eventOf	[Pathway:R-GGA-421178] Urate synthesis - Gallus gallus
followingEvent	[Reaction:R-GGA-421158] xanthine + H2O + NAD+ => urate + NADH + H+ - Gallus gallus
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-113599] Hyp [cytosol] [SimpleEntity:R-ALL-29360] NAD+ [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:421170] Purification and characterization of chicken liver xanthine dehydrogenase [LiteratureReference:421175] The oxidation of reduced xanthine dehydrogenase in chicken liver [LiteratureReference:421182] The structure of chicken liver xanthine dehydrogenase. cDNA cloning and the domain structure [LiteratureReference:422405] Xanthine oxidase in different species
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	hypoxanthine + H2O + NAD+ => xanthine + NADH + H+
output	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-73473] NADH [cytosol] [SimpleEntity:R-ALL-30064] XAN [cytosol]
precedingEvent	[Reaction:R-GGA-421174] inosine + orthophosphate <=> hypoxanthine + D-ribose 1-phosphate - Gallus gallus
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-421161
summation	[Summation:421156] Cytosolic xanthine dehydrogenase (XDH) catalyzes the reactio...

Referrals

(hasEvent)	[Pathway:R-GGA-421178] Urate synthesis
(precedingEvent)	[Reaction:R-GGA-421158] xanthine + H2O + NAD+ => urate + NADH + H+

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