Reactome | Formation of PPAT tetramers

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Formation of PPAT tetramers Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:420913] D'Eustachio, P, 2009-05-14 17:32:05
dbId	420906
displayName	Formation of PPAT tetramers
eventOf	[Pathway:R-GGA-419140] De novo synthesis of IMP - Gallus gallus
input	2 × [Complex:R-GGA-420912] PPAT dimer [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:420910] Glutamine phosphoribosylpyrophosphate amidotransferase. Catalytic and conformational heterogeneity of the pigeon liver enzyme [LiteratureReference:111231] Human glutamine phosphoribosylpyrophosphate amidotransferase. Two molecular forms interconvertible by purine ribonucleotides and phosphoribosylpyrophosphate [LiteratureReference:420914] Phosphoribosyl pyrophosphate amidotransferase. Purification and general catalytic properties [LiteratureReference:420909] The enzymology of feedback inhibition of glutamine phosphoribosylpyrophosphate amidotransferase by purine ribonucleotides
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Formation of PPAT tetramers
output	[Complex:R-GGA-420903] PPAT tetramer [cytosol]
regulatedBy	[PositiveRegulation:R-GGA-420921] Positive regulation by 'guanosine 5'-monophosphate [cytosol]' [PositiveRegulation:R-GGA-420922] Positive regulation by 'adenosine 5'-monophosphate [cytosol]' [NegativeRegulation:R-GGA-420923] Negative regulation by 'PRPP [cytosol]'
releaseDate	2008-06-30
reverseReaction	[Reaction:R-GGA-420911] Formation of PPAT dimers
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-420906
summation	[Summation:420905] Biochemical characterization of purified avian PPAT (chicken...

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(hasEvent)

[Pathway:R-GGA-419140] De novo synthesis of IMP