Reactome | SETDB1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-GGA-9844105] me3-K16-ATF7IP:SETDB1 [nucleoplasm] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-5159250] ATF7IP binds SETDB1 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10787740
displayName	SETDB1 [nucleoplasm]
endCoordinate	1291
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-417136] SETDB1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	SETDB1 SETDB1 A0A8V1AH56
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8V1AH56] UniProt:A0A8V1AH56
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49591] Gallus gallus
stId	R-GGA-417136
startCoordinate	1

(activeUnit)	[CatalystActivity:10821997] histone H3 methyltransferase activity of me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3:Nucleosome with H3K9me3 [nucleoplasm] [CatalystActivity:10821984] histone H3 methyltransferase activity of me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA [nucleoplasm] [CatalystActivity:10821428] histone H3 methyltransferase activity of ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement chromatin [nucleoplasm]
(hasComponent)	[Complex:R-GGA-9844105] me3-K16-ATF7IP:SETDB1 [nucleoplasm] [Complex:R-GGA-5159246] ATF7IP:SETDB1 [nucleoplasm]
(input)	[Reaction:R-GGA-5159250] ATF7IP binds SETDB1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-417136] SETDB1 [nucleoplasm]

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