Reactome | TNKS1/2 [cytosol]

Schema > DefinedSet > Entries

catalystActivities	[CatalystActivity:10811166] NAD+ poly-ADP-ribosyltransferase activity of TNKS1/2 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-GGA-3640822] AXIN:TNKS [cytosol] - Gallus gallus
consumedByEvent	[Reaction:R-GGA-3640862] Tankyrase binds AXIN - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10785289
displayName	TNKS1/2 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-GGA-3640824] TNKS2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-3640825] TNKS [cytosol] - Gallus gallus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-3640826] TNKS1/2 [cytosol] - Homo sapiens
maxDepth	2
name	TNKS1/2
producedByEvent	[BlackBoxEvent:R-GGA-3640874] Ub-RibC-AXIN is degraded by the proteasome - Gallus gallus
schemaClass	DefinedSet
species	[Species:49591] Gallus gallus
stId	R-GGA-3640826

(output)	[BlackBoxEvent:R-GGA-3640874] Ub-RibC-AXIN is degraded by the proteasome
(activeUnit)	[CatalystActivity:10785302] NAD+ poly-ADP-ribosyltransferase activity of AXIN:TNKS [cytosol]
(input)	[Reaction:R-GGA-3640862] Tankyrase binds AXIN
(hasComponent)	[Complex:R-GGA-3640822] AXIN:TNKS [cytosol] [Complex:R-GGA-3772504] RibC-AXIN:TNKS [cytosol] [Complex:R-GGA-3640854] Ub-RibC-AXIN:TNKS:RNF146 [cytosol]
(physicalEntity)	[CatalystActivity:10811166] NAD+ poly-ADP-ribosyltransferase activity of TNKS1/2 [cytosol]
(inferredTo)	[DefinedSet:R-HSA-3640826] TNKS1/2 [cytosol]

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