Reactome | PI3K associates with phosphorylated GAB2

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PI3K associates with phosphorylated GAB2 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10782872
displayName	PI3K associates with phosphorylated GAB2
eventOf	[Pathway:R-GGA-2730905] Role of LAT2/NTAL/LAB on calcium mobilization - Gallus gallus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-GGA-2730870] Phosphorylation of PIP2 to PIP3 by PI3K - Gallus gallus
inferredFrom	[Reaction:R-HSA-2730842] PI3K associates with phosphorylated GAB2 - Homo sapiens
input	[Complex:R-GGA-2685687] p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2 [plasma membrane] [Complex:R-GGA-74693] PI3K [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PI3K associates with phosphorylated GAB2
output	[Complex:R-GGA-2685700] p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2730842
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-GGA-2730905] Role of LAT2/NTAL/LAB on calcium mobilization
(precedingEvent)	[Reaction:R-GGA-2730870] Phosphorylation of PIP2 to PIP3 by PI3K
(inferredTo)	[Reaction:R-HSA-2730842] PI3K associates with phosphorylated GAB2

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