Reactome | CREG(CR1L) binds to surface-bound C3 convertases

Schema > Reaction > Entries

CREG(CR1L) binds to surface-bound C3 convertases Show undefined attributes

authored	[InstanceEdit:2869458] Shamovsky, V, 2012-12-20
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2530587] Shamovsky, V, 2012-10-17
dbId	2530573
displayName	CREG(CR1L) binds to surface-bound C3 convertases
edited	[InstanceEdit:5149549] Shamovsky, V, 2013-11-19
eventOf	[Pathway:R-GGA-2132281] Regulation of complement cascades - Gallus gallus
followingEvent	[Reaction:R-GGA-2530591] CREG (CR1L) causes dissociation of C3 convertases - Gallus gallus
inferredFrom	[Reaction:R-HSA-977375] CR1 binds C3bBb/C4bC2a - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-GGA-2132089] CREG [plasma membrane] [DefinedSet:R-GGA-2132242] surface-bound C3 convertases [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:2530555] Regulator of complement activation (RCA) locus in chicken: identification of chicken RCA gene cluster and functional RCA proteins [LiteratureReference:2530563] A novel chicken membrane-associated complement regulatory protein: molecular cloning and functional characterization
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CREG(CR1L) binds to surface-bound C3 convertases
output	[DefinedSet:R-GGA-2530582] CREG:C3 convertases [plasma membrane]
precedingEvent	[Reaction:R-GGA-2132074] Cleavage of surface-bound factor B - Gallus gallus [Reaction:R-GGA-2132222] Cleavage of factor B to form classical C3 convertase - Gallus gallus
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562608] D'Eustachio, P, 2012-11-06 [InstanceEdit:3006589] Jupe, S, 2013-01-31
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2530573
summation	[Summation:2530580] Gene encoding complement regulatory GPI-anchored protein (CR...

Referrals

(precedingEvent)	[Reaction:R-GGA-2530591] CREG (CR1L) causes dissociation of C3 convertases
(hasEvent)	[Pathway:R-GGA-2132281] Regulation of complement cascades
(inferredTo)	[Reaction:R-HSA-977375] CR1 binds C3bBb/C4bC2a

Cite Us!