Reactome | C4b binds to target cell surface

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C4b binds to target cell surface Show undefined attributes

authored	[InstanceEdit:2869458] Shamovsky, V, 2012-12-20
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:2132255] Shamovsky, V, 2012-02-21
dbId	2132248
deleted	[Deleted:5605096] Deletion of instance: 2859049
displayName	C4b binds to target cell surface
edited	[InstanceEdit:5149549] Shamovsky, V, 2013-11-19
eventOf	[Pathway:R-GGA-2132263] Creation of classical C3 convertase - Gallus gallus
followingEvent	[Reaction:R-GGA-2132096] Formation of C4b:factor B complex - Gallus gallus
inferredFrom	[Reaction:R-HSA-981713] C4b binds to cell surface - Homo sapiens
input	[DefinedSet:R-GGA-2132172] C4b [extracellular region] [OtherEntity:R-ALL-2132109] Cell-surface carbohydrates [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:2132161] An assay for measuring the mannan-binding lectin pathway of complement activation in chickens
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	C4b binds to target cell surface
output	[Complex:R-GGA-2132117] C4b [plasma membrane]
precedingEvent	[BlackBoxEvent:R-GGA-2132233] Proteolytic cleavage of complement factor C4 - Gallus gallus
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2562608] D'Eustachio, P, 2012-11-06 [InstanceEdit:3006589] Jupe, S, 2013-01-31
schemaClass	Reaction
species	[Species:49591] Gallus gallus
stId	R-GGA-2132248
summation	[Summation:2132236] Cleavage of C4 exposes an active thioester bond on the large...
updateTrackers	[UpdateTracker:9785973] Update Tracker - [Reaction:2132248] C4b binds to target cell surface - v50:[removeRegulator]

Referrals

(updatedInstance)	[UpdateTracker:9785973] Update Tracker - [Reaction:2132248] C4b binds to target cell surface - v50:[removeRegulator]
(replacementInstances)	[Deleted:5605096] Deletion of instance: 2859049
(hasEvent)	[Pathway:R-GGA-2132263] Creation of classical C3 convertase
(precedingEvent)	[Reaction:R-GGA-2132096] Formation of C4b:factor B complex
(inferredTo)	[Reaction:R-HSA-981713] C4b binds to cell surface

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