Reactome | HS/HPIN-PGs [lysosomal lumen]

Schema > DefinedSet > Entries

compartment	[Compartment:161320] lysosomal lumen
consumedByEvent	[Reaction:R-GGA-1667005] Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome) - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10774047
displayName	HS/HPIN-PGs [lysosomal lumen]
hasMember	[EntityWithAccessionedSequence:R-GGA-2090035] GPC1 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090067] GPC3 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090073] GPC4 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090029] GPC5 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090051] GPC6 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090082] SDC1 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090064] SDC2 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090065] SDC3 [lysosomal lumen] - Gallus gallus [EntityWithAccessionedSequence:R-GGA-2090058] SDC4 [lysosomal lumen] - Gallus gallus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-2090050] HS/HPIN-PGs [lysosomal lumen] - Homo sapiens
maxDepth	2
name	HS/HPIN-PGs Heparan sulfate/heparin-PGs
producedByEvent	[BlackBoxEvent:R-GGA-2024084] HS-GAGs translocate to the lysosome for degradation - Gallus gallus
schemaClass	DefinedSet
species	[Species:49591] Gallus gallus
stId	R-GGA-2090050

(input)	[Reaction:R-GGA-1667005] Heparanase (HPSE) cleaves heparan sulfate from its proteoglycan (lysosome)
(output)	[BlackBoxEvent:R-GGA-2024084] HS-GAGs translocate to the lysosome for degradation
(inferredTo)	[DefinedSet:R-HSA-2090050] HS/HPIN-PGs [lysosomal lumen]